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KMID : 0604520210470010023
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Journal of the Society of Cosmetic Scientists of Korea
2021 Volume.47 No. 1 p.23 ~ p.30
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A Study on the Activities of Five Natural Plant Essential Oils on Atopic Dermatitis
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Jeong Jeong-Hwa
Nguyen Thao Kim Nu
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Abstract
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This study is an experiment to evaluate the anti-atopy efficacy of five kinds of natural plant essential oils; Artemisia annua L. (AA), Citrus junos Sieb. ex TANAKA (CJ), Chrysanthemum boreale Makino (CB), Pinus koraiensis (PK), and Pinus densiflora for. erecta (PD). Through Agar diffusion test, five species of native plant essential oils were treated in a total of four strains, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans. In order to invest the anti-inflammatory effect, five kinds of natural plant essential oils were treated in HaCaT cells-induced by TNF-α and IFN-γ (TI). AA, CJ, CB, PK and PD showed antibacterial effects on Candida albicans at a concentration of 10 mg/mL. We also found that the thymus and activation-regulated chemokine (TARC) expression was suppressed in 0.1 μg/mL of PK, 1 μg/mL of AA, CB, and PK. macrophage-derived chemokine (MDC) expression was suppressed in 1 μg/mL of AA and PK. IL-6 expression was suppressed in 0.1, 1 μg/mL of AA, PK in HaCaT cells. Hence it suggests that AA, CB, and PK have the anti-inflammatory effects, and it could contribute to atopic dermatitis relief by reducing the infiltration of immune cells to inflamed area.
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KEYWORD
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native plant, essential oil, atopic dermatitis, anti-microbial, anti-inflammation
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